NINAVELI Exogen Complex (1 x 5mL)
NINAVELI EXOGEN Complex is our unique Advanced bio-signalling formula containing Exosomes, Polynucleotides (PDRN), and Essential Bio-Actives. Designed to support skin vitality, promote the appearance of a rejuvenated complexion, and help maintain the skin’s natural structural resilience. By combining the regenerative power of Centella Asiatica Exosomes and Sodium DNA with the brightening capabilities of Niacinamide and Glutathione, this solution delivers immediate radiance while promoting long-term firmness and hydration.
Key features and cosmetic benefits
- SCPN & CPNP certified:
- Manufactured in GMP (ISO 22716) & QMS (ISO 13485) certified facility
- Dermatologically tested
- Promotes a renewed, revitalized complexion to combat signs of skin fatigue
- Refines overall skin texture for a smoother, more uniform appearance
- Enhances the feeling of skin density and natural elasticity
- Strengthens the look of the skin barrier for improved resilience
Specification
- Active Ingredients: Exosomes, Polynucleotides (PN), Niacinamide, Glutathione, Adenosine, Peptides, Biotin, Hyaluronic Acid
- Packaging: 1 vial x 5mL / box
- Manufacturer: NINAVELI LONDON LIMITED
Active Ingredients
- Exosomes
- Polynucleotides
- Niacinamide
- Glutathion
- Adenosine
- Peptides
- Biotin
Scientific Context
- Centella Asiatica Exosomes are nano-sized extracellular vesicles derived from plant stem cells that function as potent mediators of cell-to-cell communication. Scientific research indicates they are rich in lipids, proteins, and RNA, capable of modulating inflammation and stimulating tissue regeneration by delivering bioactive molecules directly to dermal fibroblasts.
- Polynucleotides (Sodium DNA) are DNA fragments derived from salmon germ cells that act as regenerative agents within the dermis. Evidence suggests they activate adenosine A2A receptors, stimulating fibroblast proliferation and increasing collagen synthesis to improve overall skin thickness and elasticity.
- Niacinamide (Vitamin B3) is a water-soluble vitamin well-documented for its ability to strengthen the skin barrier by upregulating ceramide synthesis. Clinical studies also demonstrate its efficacy as a brightening agent, functioning by inhibiting the transfer of melanosomes from melanocytes to keratinocytes, thereby reducing visible pigmentation.
- Glutathione is a powerful tripeptide antioxidant essential for cellular defense against oxidative stress. Its depigmenting mechanism is backed by evidence showing it directly inhibits the enzyme tyrosinase, shifting the pigmentation pathway toward the production of lighter pheomelanin to promote an even skin tone.
- Adenosine is a naturally occurring nucleoside that plays a key role in cellular energy metabolism. Research published in the International Journal of Cosmetic Science highlights its anti-aging benefits, noting its ability to energize the skin surface and significantly reduce the appearance of periorbital wrinkles (crow’s feet) and glabellar lines.
- Biomimetic Peptides (Copper Tripeptide-1, Palmitoyl Pentapeptide-4) are signalling molecules designed to mimic the skin’s natural repair mechanisms. Palmitoyl Pentapeptide-4 is clinically shown to stimulate the production of collagen I, III, and IV, while Copper Tripeptide-1 aids in tissue remodeling and anti-inflammatory processes to restore structural integrity.
- Sodium Hyaluronate is the salt form of hyaluronic acid, known for its superior stability and penetrative ability. It binds massive amounts of water in the extracellular matrix, providing immediate deep hydration that plumps the skin and facilitates the effective transport of other active ingredients into the epidermis.