NINAVELI PDRN Pro Advanced Serum (1 x 50mL)
NINAVELI PDRN Pro Advanced Serum is a unique formulation that bridges the gap between clinical treatments and home care. Dermatologically tested, this advanced serum combines a high 1% Sodium DNA concentration, 4% Panthenol, and a winning dual-weight Hyaluronic Acid matrix to deliver a powerful soothing complex. It is engineered to intensively repair the skin barrier, rapidly reduce redness, and effectively maintain the beautiful results of professional skin booster treatments.
Key features and cosmetic benefits
- SCPN & CPNP certified:
- Manufactured in GMP (ISO 22716) & QMS (ISO 13485) certified facility
- Dermatologically tested
- High concentration of PDRN (10,000ppm) for powerful tissue repair and regeneration
- Perfectly suited for post procedure care and recovery
- Rapidly reduced redness and irritation for calming and soothing effect
- Enhances moisture retention capabilities for a noticeably plump and firm look
- Restores the lipid barrier to prevent water loss and sensitivity
- Penetrates deep layers while pumping the surface for complete dual depth hydration
Specification
- Active Ingredients: Sodium DNA (PDRN), Dual-Weight Hyaluronic Acid (HA), Panthenol (Vitamin B5), Niacinamide (Vitamin B3), Madecassoside & Asiaticoside (Centella Asiatica Complex)
- Packaging: 1 x 50mL / box
- Manufacturer: NINAVELI LONDON LIMITED
Active Ingredients
- Sodium DNA (PDRN)
- Dual-Weight Hyaluronic Acid (HA)
- Panthenol (Vitamin B5)
- Niacinamide (Vitamin B3)
- Madecassoside & Asiaticoside (Centella Asiatica Complex)
Scientific Context
- Sodium DNA (PDRN) consists of Polydeoxyribonucleotides, which are purified, low molecular weight DNA fragments sourced from salmon germ cells that exhibit high compatibility with human DNA. The therapeutic and cosmetic efficacy of PDRN is well-documented in scientific literature, including the Journal of Cosmetic Dermatology, and is primarily attributed to its mechanism as a signaling molecule: PDRN acts on A2A adenosine receptors on the surface of dermal cells, which triggers the robust proliferation of fibroblasts—the cells responsible for producing structural proteins and subsequently enhances the synthesis of collagen and elastin, leading to observed benefits like increased dermal density and improved skin elasticity.
- Dual-Weight Hyaluronic Acid (HA) is an advanced delivery system formulated with both Low Molecular Weight (L-MW)and Medium Molecular Weight (M-MW) HA to deliver comprehensive hydration and regenerative benefits across the epidermis. Scientific literature, including publications in the Journal of Clinical and Aesthetic Dermatology, provides evidence that this combination strategy is key: the L-MW HA is small enough to penetrate the deeper layers of the epidermis to stimulate collagen and promote long term elasticity and repair, while the M-MW HA focuses its action in the mid layers, ensuring sustained hydration, improved texture, and the reinforcement of the skin barrier.
- Panthenol (Vitamin B5) functions as a potent humectant and emollient, providing essential hydration and skin softening benefits. Scientific evidence confirms that at concentrations of 1% and above of Panthenol is clinically proven to significantly reduce transepidermal water loss (TEWL), thereby maintaining and reinforcing the skin’s integrity. It is widely recognized in dermatological research for its ability to speed up wound healing, making it an outstanding ingredient for calming, repair, and post-procedure care.
- Niacinamide (Vitamin B3) is a highly versatile cell communicating ingredient that is essential for cellular energy and repair functions within the skin. Scientific evidence, including research published in the International Journal of Cosmetic Science, demonstrates that Niacinamide significantly improves the skin barrier by actively stimulating the synthesis of vital components like ceramides and free fatty acids. It is clinically proven to deliver visible cosmetic benefits, including the inhibition of melanosome (pigment) transfer, which leads to a noticeably brighter, more even complexion, along with effective regulation of excess oil production.
- Madecassoside & Asiaticoside (Centella Asiatica Complex) is sourced from the botanical known as “Tiger Grass.” These compounds are widely recognized for their potent anti inflammatory properties, which rapidly soothe and calm reactive or compromised skin. Scientific research confirms these triterpenes also play a crucial role in active tissue regeneration by stimulating the production of Type I and Type III collagen, thereby supporting skin repair and improving dermal firmness